Non-Steady-State Phenytoin Features

• Oral doses are input as a constant 60 mg/hour regardless of dose to better model absorption.

• Parameter estimations use the most up-to-date documented methods which are fully documented and referenced in the User Manual.

• Covers all age ranges, renal function, serum albumin, patient weight variations and factors that modify parameters.

• Curve fitting calculates concentration at time (t) using an exact iterative calculation, not the commonly used approximation method.

• Bayesian fitting of up to 9 serum levels ensures the best fitting accuracy.

• Familiar simple data input screens, same as other drugs.